Knowledgeable
Use case · EU HTA JCA

EU HTA Joint Clinical Assessment

Joint Clinical Assessment, and every local adaptation, in one workflow.

Knowledgeable runs the centralised EU JCA dossier and every country-level adaptation from the same evidence base, so the PICO scoping, comparator matrix and clinical benefit narrative you submit to the Coordination Group is the one your German, French and Italian teams can defend the week after.

All Member States
PICOs handled in parallel
Same evidence base
central-to-local reuse
Days
from JCA to national dossier
Knowledgeable Live

Watch it run on your work.

Director, Market Access
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Grounded in 9 sources · audit-logged
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Background & context

Where this fits in your workflow.

Knowledgeable runs the centralised EU JCA dossier and every country-level adaptation from the same evidence base, so the PICO scoping, comparator matrix and clinical benefit narrative you submit to the Coordination Group is the one your German, French and Italian teams can defend the week after.

Most teams running EU HTA · JCA today juggle a stack of search tools, PDF readers and consultancy slides, then spend the back half of the project reconciling claims to sources. Knowledgeable collapses that into one defensible workflow: joint clinical assessment, and every local adaptation, in one workflow.

The work runs against your literature, trial registries, HTA precedent, label and SmPC, with every sentence pinpoint-cited so your senior reviewer opens a document that's already at QC.

Evidence sources
Published literatureTrial registriesHTA precedentLabel / SmPCConference abstractsReal-world data
How it runs
  1. 1Scope & comparator locked
  2. 2Evidence pulled & graded
  3. 3Draft built with citations
  4. 4QC pass against framework
What changes

The work that finally lands the way you scoped it.

Multi-PICO from day one

Every Member State PICO addressed in the same evidence workspace, not bolted on after the Coordination Group asks.

All PICOs · one dossier

Central-to-local traceability

Every national adaptation inherits the JCA evidence chain, with local additions clearly marked.

Traceable

Coordination Group aware

Structure, timelines and evidence expectations aligned to the current JCA guidance, not last year's draft.

Regulation-aligned

One narrative, many markets

Clinical benefit story that survives translation into AMNOG, HAS, AIFA and beyond without three rewrites.

Cross-HTA coherent

Land the JCA once, launch nationally on the same evidence.

Scope a JCA submission
Responsible AI · Enterprise security

Built for the EU HTA regime.

Aligned to the EU HTA Regulation, source-linked, audit-trailed. Ready for the Coordination Group and every national body downstream.

Designed to align with the EU AI ActSSO + MFAAES-256 + TLS 1.2+EU / UK data residencyFull audit trail
Pre-answered for InfoSec, MLR and procurement.