Knowledgeable
The platform

Every surface your team needs. Connected.

From structured search through to final deliverable, all in one operational environment. Grounded in your evidence. Governed by default. Faster from your first project.

Sources
PubMed
ClinicalTrials.gov
OpenAlex
HTA bodies
Pricing DBs
Knowledgeable engine
Ontology
Grounded AI
Workflow surfaces
Outputs
HTA dossiers
Value stories
TPPs
Insights
Dashboards
Continuous flow · every output enriches the system
Architecture

Built across four connected layers.

Each layer is useful on its own. Together they create a system that gets better every time someone uses it.

Layer 01
Evidence
Unified foundation
TrialsRWEHTAPricingGuidelines
Layer 02
Ontology
Connective tissue
Concept graphProvenanceAuditability
Layer 03
Workflow
How work happens
SearchHubsCollectionsProjects
Layer 04
Intelligence
Grounded AI
SummarisationReviewPHTATPP
Evidence
Ontology
Workflow
Intelligence
How you work

Every module is fully usable by hand. Ask Knowledgeable is one keystroke away on every surface. Use it for everything, nothing, or just the bits where it helps.

Manual ↔ chat
Modules

Six surfaces. One source of truth.

Six environments your team works in every day. All sharing the same evidence and ontology underneath.

HEOR analysts, evidence leads

Search Strategies

Structured, repeatable evidence retrieval across PubMed, OpenAlex, ClinicalTrials.gov and HTA sources. AI term expansion, gap analysis and cross-source translation built in.

Cross-functional Access teams

Knowledge Hubs

Collaborative spaces where evidence is connected, interpreted and transformed into shared contextual understanding.

Project leads, programme managers

Projects

Execution environments for HTA submissions, value dossiers, literature reviews and pricing strategy. Structured workstreams, not free-form folders.

Evidence specialists, reviewers

Evidence Collections

Scoped workspaces for PICO setup, deduplication, dual-reviewer screening, PRISMA tracking and conflict resolution.

Heads of Access, HEOR directors

Dashboards

Operational coordination across projects, tasks, reviews and audit history in one connected surface.

Everyone, every surface

Ask Knowledgeable

Your intelligence AI agent. Two modes, Ask for quick, cited answers and summaries; Build to plan, execute and QC the work, orchestrating your Search Strategies, Evidence Collections, Knowledge Hubs and prior project outputs into a structured, sourced answer, building on what your team has already done rather than starting from scratch.

Intelligence layer

AI grounded in your evidence, your ontology, your prior work.

Knowledgeable's AI doesn't sit on top of your workflows. It lives inside them. Every suggestion is traceable to a source. Every output is reviewable, defensible and private to your organisation.

Private by default, RBAC throughout
Grounded inside your organisation's boundary, never a shared public model layer. Role-based access controls scope evidence, projects and AI actions across organisations, teams and individual reviewers.
Traceable
Every claim links back to the evidence that produced it.
Human-in-the-loop
Validation and interpretation stay part of structured human-led workflows.

Evidence Summarisation

AI-drafted component narratives grounded in linked references.

Review Suggestions

Relevance predictions with PICO reasoning and confidence.

Pricing & HTA Analysis

Cross-country decisions, restrictions, prices and benchmarks.

TPP Builder

Structured Target Product Profiles tied back to live evidence.

Indication Assessment

Opportunity scoring across indication landscape.

Cost-Effectiveness

Modelling assistance anchored to validated inputs.

The result

A live operating picture of your evidence.

One dashboard that ties every project, every reviewer and every insight into a single audit-ready surface.

knowledgeable.ai / dashboard
● live
0
Active projects
0
Insights this week
0h
Hours saved
Output velocity
+312%
Activity feed
Search strategy auto-expanded
+38 new refs
Knowledge hub merged
EU5 payer evidence
HTA decision indexed
G-BA · 11 min ago
Reviewer agreement
94% concordance
Compounding

Better the second time. Better still the tenth.

Nothing gets lost between people or projects. Every decision, comment and citation stays attached to the evidence, teammates are notified when something they own moves, and each completed project adds validated evidence, ontology refinements and reasoning patterns back into the system. The next analyst starts further ahead than the last one finished.

Evidence
Ontology
AI
Outputs
Compounds

See the platform in action.

Book a demo
FAQ

Frequently asked questions.

Knowledgeable is an AI operating system for Market Access, HEOR and Evidence teams. It connects four layers, evidence, ontology, workflow and intelligence, so search strategies, knowledge hubs, projects, evidence collections, dashboards and Ask Knowledgeable all share one source of truth.
Responsible AI · Enterprise security

Built for regulated environments.

Designed to align with the EU AI Act, GDPR-aligned, SSO with 2FA enforced, encryption everywhere and a full audit trail on every action. Security isn't a tier. It's the floor.

Designed to align with the EU AI ActGDPR / UK GDPRSSO + MFA enforcedAES-256 + TLS 1.2+EU / UK data residencyNo training on your dataFull audit trail