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evidence-data· 4 June 2026· 4 min read

ITC pre-registration plan

Pre-register your indirect comparison before the data does the talking.

Author
Charlie Brook, Chief Innovation Officer
Chief Innovation Officer
Knowledgeable

Reviewers tear unanchored MAICs apart when the choice of effect modifiers looks post-hoc. This template forces the decisions up front: PICO, inclusion criteria, candidate effect modifiers, primary and sensitivity analyses, reporting plan.

Download the plan

Markdown file — version it alongside your code.

Download .md