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hta-payer· 22 May 2026· 9 min read
Reading a NICE FAD without losing the plot
What the Final Appraisal Document tells you that nobody says out loud.
Author
Chief Innovation Officer
The four signals
A FAD reads like a careful committee minute. Four signals tell you what actually moved the decision: comparator framing, ERG critique acceptance, severity / end-of-life criteria, and managed access proposals.
How the committee describes the comparator — current standard of care, established management, best supportive care — tells you what they accepted as the relevant counterfactual.
Sources
- NICE methods 2022· NICE