Resources
playbooks· 24 May 2026· 12 min read
The German AMNOG clock: a week-by-week field guide
What actually happens between launch and price agreement.
Author
Chief Innovation Officer
The first 90 days
Most of the work that decides your AMNOG outcome happens before the dossier lands. The G-BA's appropriate comparator therapy (zVT) is set in stone the moment you submit. Get it wrong and IQWiG can't rescue you.
6 mo
From submission to G-BA decision
3 mo
IQWiG benefit assessment window
6 mo
Price negotiation with GKV-SV
What IQWiG actually reads
We read the comparator definition, then the endpoint hierarchy, then the subgroups. If those don't match the zVT, we're done by page 30.
The reviewer-shaped dossier
Reorder your Module 4 so the comparator, endpoint hierarchy and subgroup logic sit in the first 20 pages. That's where the assessor decides whether your dossier is serious.
Sources
- G-BA AMNOG procedure· G-BA
- IQWiG methods 6.1· IQWiG